Sam Vilsmeier wrote:

Pinky & The Brain / UY

"Gee, Darling, what do you want to do tonight?"

"The same thing I do every night."

*ZAP*  "Darling no baka!"


Another possibility:

Mihoshi & Kiyone (Tenchi Muyo) meet the Dirty Pair.  (The main
challenge writing this would be coming up with many varied and
interesting ways to say "blew up".)