On Sun, 3 Nov 1996, Lizsue wrote:

In the above situation, a certain emzyme which turns testosterone into
dyhydrotestosterone is faulty. DHT causes the formation of the lower part
of the urethra rather than a vagina and a penis rather than a clitoris,
among other things. During adolecence, the DHT is still absent, but
garden-veriety testosterone causes the former clitoris to turn into a
penis. Ie, although the Big Gene is the first link, there are things that
might go wrong.

In fact, I read somewhere that this was attempted on purpose.

Back in World War II, some Allied saboteurs decided that Hitler might be too 
distracted to fight a war if he turned female or at least "had his moustache 
fall off and turned soprano".  The plan was to make his gardener inject lots 
of estrogen, progestin, etc., into the food.

Really? So what happened? :) (But if they have access to Hitler's food, 
why not just inject it with poison? Its a surer way of stopping him. :)